Concurrent Chemoradiotherapy Increases the Levels of Soluble Immune Checkpoint Proteins in Patients with Locally Advanced Cervical Cancer
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چکیده
منابع مشابه
Concurrent Chemoradiotherapy without Brachytherapy in Locally Advanced Cervical Cancer
BACKGROUND Concurrent chemoradiotherapy (EBRT + cisplatin) plus intracavitary brachytherapy is the standard of care in patients with advanced cervical cancer. However, a number of patients could not undergone brachytherapy due to massive residual tumor or anatomical distortion. In this study, we have evaluated the treatment outcome in patients with locally advanced cervical cancer, undergone co...
متن کاملconcurrent chemoradiotherapy without brachytherapy in locally advanced cervical cancer: a phase ii clinical trial
background and objective: concurrent chemoradiotherapy (ebrt + cisplatin) plus intracavitary brachytherapy is the standard of care in patients with advanced cervical cancer. however, some patients are unable to undergo brachytherapy due to massive residual tumor or anatomical distortion. in this study, we evaluated the treatment outcome in patients with locally advanced cervical cancer undergoi...
متن کاملExtrafascial hysterectomy after concurrent chemoradiotherapy in locally advanced cervical adenocarcinoma
OBJECTIVE To evaluate whether adjuvant simple hysterectomy after concurrent chemoradiotherapy (CCRT) improves progression-free survival (PFS) compared with current standard care in locally advanced cervical adenocarcinoma (LACAC). METHODS We reviewed a cohort of 55 patients with LACAC (International Federation of Gynecology and Obstetrics [FIGO] stage IB2, IIA2, IIB, III without distant metas...
متن کاملImpact of adjuvant hysterectomy on prognosis in patients with locally advanced cervical cancer treated with concurrent chemoradiotherapy: a meta-analysis
OBJECTIVE Few data exist regarding adjuvant hysterectomy (AH) in locally advanced cervical cancer (LACC) patients treated with chemoradiotherapy. We investigated the effect of AH on prognosis in LACC patients, through meta-analysis. METHODS EMBASE and MEDLINE databases and the Cochrane Library were searched for published studies comparing LACC patients who received AH after chemoradiotherapy ...
متن کاملTreatment outcome of cisplatin-based concurrent chemoradiotherapy in the patients with locally advanced nasopharyngeal cancer.
PURPOSE The standard treatment of locally advanced nasopharyngeal cancer is a concurrent chemoradiotherapy (CCRT), and cisplatin has been used as the most popular chemotherapeutic agent. But many different doses and schedules for cisplatin administration such as daily, weekly and 3 week cycles have been proposed. We compared and analyzed the tumor response, the overall survival, the toxicity an...
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ژورنال
عنوان ژورنال: International Journal of Radiation Oncology*Biology*Physics
سال: 2020
ISSN: 0360-3016
DOI: 10.1016/j.ijrobp.2020.07.2303